Translocation of BCR ABL gene chromosome 9 to 22 , chronic myeloid leukemia

Topic: Discuss the pathological and prognostic impact of gene fusion in blood cancer.Key points:1- the normal function of gene before the fusion event2- the altered function of gene post fusion3-How the altered function of fused genes affects the disease progression/initiation4- How the altered function of fused genes affects the disease prognosis5- Text paraphrasing should be applied as the text will be scanned for text similarity6- Make a good use of referencing system of your choice8 the format of the text is: Abstract–> introduction–>body of the topic —> conclusion.9- Reference should include text books and papers.

 

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